Publications

  • Tanaka, Hayakawa and Teshima. 2023. Power of neutrality tests for detecting natural selection.  G3: Genes|Genomes|Genetics, jkad161
    • ゲノム多様性情報を解析して、適応進化を受けたかどうかを調べることができます。それらの方法は注目する多様性や計算方法に違いがあることから、それぞれの方法で検出できる適応進化は異なります。この研究ではシミュレーションを行なって仮想的に適応進化を発生させ、さまざまな検出方法の検出効率を測定して検出できる適応の違いを調べました。比較的最近に生じた適応を検出しやすい方法や、古い時代に生じた適応まで検出できる方法など、方法ごとの検出特性の違いを議論しました。
  • Hayakawa et al. 2021. Lower promoter activity of the ST8SIA2 gene has been favored in evolving human collective brains. PLoS ONE 16(12): e0259897
  • Mukasyaf et al. 2021. Development and Characterization of EST-SSR Markers for Pinus ThunbergiiJournal of Forest Research, August, 1–4.
  • Dokan et al. 2021, Effects of single nucleotide polymorphism ascertainment on population structure inferences. G3: Genes|Genomes|Genetics
    • ゲノム多様性データの取得が一般的になりました。しかし取得方法によってはデータにバイアスが入ります。この研究ではタイピングデータを念頭に置いて、その取得デザインとバイアスの影響について考察しました。その結果、タイピングデータは予備調査で用いるサンプル(パネルサンプル)の影響を強く受けることがわかりました。特に集団構造の解析では解析結果が大きく歪みうることを示し、この歪みを防ぐためのデータ取得法を提案しました。
  • Hirata et al. 2021, Evaluating the genetic diversity in two tropical leguminous trees, Dalbergia cochinchinensis and D. nigrescens, in lowland forests in Cambodia and Thailand using MIG-seq. Genes Genet. Syst. 96: 41-53
  • Satta et al. Two-dimensional site frequency spectrum for detecting, classifying and dating incomplete selective sweeps. Genes Genet. Syst., 2019, 94, 283-300.
  • Yamauchi et al., Autophagy controls reactive oxygen species homeostasis in guard cells that is essential for stomatal opening. PNAS, 2019, 116, 19187-19192
  • Moriguchi et al., 2019, Inferring the demographic history of Japanese cedar, Cryptomeria japonica, using amplicon sequencing. Heredity, 123: 371-383
  • Satake et al., Field transcriptome revealed a novel relationship between nitrate transport and flowering in Japanese beech. Scientific reports, 2019, 9: 4325
  • Nakabayashi et al., The potential role of temperate Japanese regions as refugia for the coral Acropora hyacinthus in the face of climate change. Scientific Reports, 2019, 9: 1892
  • Nakamura et al. Effects of cyclic changes in population size on neutral genetic diversity. Ecology and Evolution, 2018, 8:9362-9371
  • Hiraoka et al. Potential of genome-wide studies in unrelated plus trees of a coniferous species, Cryptomeria japonica (japanese cedar).  Frontiers in Plant Science, 2018, 9
  • Fujito et al. A new inference method for detecting an ongoing selective sweep. Genes Genet. Syst., 2018, 93, 149-161.
  • Fujito et al. Positive selection on schizophrenia-associated ST8SIA2 gene in post-glacial Asia. PLoS ONE, 2018, 13, e0200278.
  • Hayakawa et al. Coevolution of Siglec-11 and Siglec-16 via gene conversion in primates. BMC Evol. Biol., 2017, 17, 228.
  • Ikezaki et al. Inferences of population structure and demographic history for Taxodium distichum, a coniferous tree in North America, based on Amplicon sequencing analysis. American Journal of Botany, 2016, 103: 1937-1949
  • Ng et al. Closely related and sympatric but not all the same: genetic variation of Indo-West Pacific Rhizophora mangroves across the Malay Peninsula. Conservation genetics, 2015, 16: 137—150
  • Urashi et al. Inferences of evolutionary history of a widely distributed mangrove species, Bruguiera gymnorrhiza, in the Indo-West Pacific region. Ecology and evolution, 2013, 7: 2251—2261
  • Iwanaga et al. Population structure and demographic history of a tropical lowland rainforest tree species Shorea parvifolia (Dipterocarpaceae) from Southeastern Asia. Ecology and evolution, 2012, 7: 1663—1675
  • Teshima, KM and Innan, H., The coalescent with selection on copy number variants. Genetics, 2012, 190: 1077—1086
  • Wang et al. Specific inactivation of two immunomodulatory SIGLEC genes during human evolution. Proc. Natl. Acad. Sci. USA, 2012, 109, 9935-9940.
  • Wang et al. Evolution of Siglec-11 and Siglec-16 genes in Hominins. Mol. Biol. Evol., 2012, 29, 2073-2086.
  • Takahashi et al. Variations in Hd1 proteins, Hd3a promoters, and Ehd1 expression levels contribute to diversity of flowering time in cultivated rice. Proceedings of the National Academy of Sciences USA, 2009, 106: 4555—4560, 2009
  • Teshima, KM and Innan, H., mbs: modifying Hudson’s ms software to generate samples of DNA sequences with a biallelic site under selection. BMC bioinformatics, 2009, 10: 166
  • Blekhman et al. Natural selection on genes that underlie human disease susceptibility. Current biology, 2008, 18: 883—889
  • Teshima, KM and Innan, H., Neofunctionalization of duplicated genes under the pressure of gene conversion. Genetics, 2008, 178: 1385—1398
  • Teshima, KM and Przeworski, M.,Directional positive selection on an allele of arbitrary dominance. Genetics, 2006, 172: 713—718
  • Teshima et al., How reliable are empirical genomic scans for selective sweeps? Genome Research, 2006, 16: 702—712
  • Hayakawa et al. Fixation of the human-specific CMP-N-acetylneuraminic acid hydroxylase pseudogene and implications of haplotype diversity for human evolution. Genetics, 2006, 172, 1139-1146.
  • Angata et al. Discovery of Siglec-14, a novel sialic acid receptor undergoing concerted evolution with Siglec-5 in primates. FASEB J., 2006, 20, 1964-1973.
  • Altheide et al. System-wide genomic and biochemical comparisons of sialic acid biology among primates and rodents: Evidence for two modes of rapid evolution. J. Biol. Chem., 2006, 281, 25689-25702.
  • Hayakawa et al. A human-specific gene in microglia. Science, 2005, 309, 1693.
  • The Chimpanzee Sequencing and Analysis Consortium. Initial sequence of the chimpanzee genome and comparison with the human genome. Nature, 2005, 437, 69-87.
  • Teshima, KM and Innan, H., The effect of gene conversion on the divergence between duplicated genes. Genetics, 2004, 166: 1553-1560
  • Teshima, KM and Tajima, F, The effect of migration during the divergence.  Theoretical population biology, 2002, 62: 81—95
  • Chou et al. Inactivation of CMP-N-acetylneuraminic acid hydroxylase occurred prior to brain expansion during human evolution. Proc. Natl. Acad. Sci. USA, 2002, 99, 11736-11741.
  • Hayakawa et al. Alu-mediated inactivation of the human CMP-N-acetylneuraminic acid hydroxylase gene. Proc. Natl. Acad. Sci. USA, 2001, 98, 11399-11404.