Differential genomic destabilisation in human cells with pathogenic MSH2 mutations introduced by genome editing.
Hayashida G, Shioi S, Hidaka K, Fujikane R, Hidaka M, Tsurimoto T, Tsuzuki T, Oda S, Nakatsu Y.
Experimental Cell Research, 377(1-2):24-35. doi: 10.1016/j.yexcr.2019.02.020.
Heterochromatin suppresses gross chromosomal rearrangements at centromeres by repressing Tfs1/TFIIS-dependent transcription.
Okita AK, Zafar F, Su J, Weerasekara D, Kajitani T, Takahashi TS, Kimura H, Murakami Y, MasukataH, Nakagawa T.
Communications Biology, 2:17. doi: 10.1038/s42003-018-0251-z.
Shelterin promotes tethering of late replication origins to telomeres for replication-timing control.
Ogawa S, Kido S, Handa T, Ogawa H, Asakawa H, Takahashi TS, Nakagawa T, Hiraoka Y, MasukataH.
EMBO Journal, 37(15). pii: e98997. doi: 10.15252/embj.201898997.
Nucleosomes around a mismatched base pair are excluded via an Msh2-dependent reaction with the aid of SNF2 family ATPase Smarcad1.
Terui R, Nagao K, Kawasoe Y, Taki K, Higashi TL, Tanaka S, Nakagawa T, Obuse C, Masukata H, Takahashi TS.
Genes&Development, 32(11-12):806-821. doi: 10.1101/gad.310995.117.
Inhibition of DNA replication by an anti-PCNA aptamer/PCNA complex.
Kowalska E, Bartnicki F, Fujisawa R, Bonarek P, Hermanowicz P, Tsurimoto T, Muszynska K, Strzalka W.
Nucleic Acids Research, 46(1):25-41. doi: 10.1093/nar/gkx1184.
Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway.
Kato N, Kawasoe Y, Williams H, Coates E, Roy U, Shi Y, Beese LS, Schärer OD, Yan H, Gottesman ME, Takahashi TS, Gautier J.
Cell Reports, 21(5):1375-1385. doi: 10.1016/j.celrep.2017.10.032.
Regulation of mitotic recombination between DNA repeats in centromeres.
Zafar F, Okita AK, Onaka AT, Su J, Katahira Y, Nakayama JI, Takahashi TS, Masukata H, Nakagawa T.
Nucleic Acids Research, 45(19):11222-11235. doi: 10.1093/nar/gkx763.
The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C).
Tsuda M, Terada K, Ooka M, Kobayashi K, Sasanuma H, Fujisawa R, Tsurimoto T, Yamamoto J, Iwai S, Kadoda K, Akagawa R, Huang SN, Pommier Y, Sale JE, Takeda S, Hirota K.
Oncotarget, 8(20):33457-33474. doi: 10.18632/oncotarget.16508.
Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ε efficiently loads the PCNA sliding clamp.
Fujisawa R, Ohashi E, Hirota K, Tsurimoto T.
Nucleic Acids Research, 45(8):4550-4563. doi: 10.1093/nar/gkx096.
Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation.
Onaka AT, Toyofuku N, Inoue T, Okita AK, Sagawa M, Su J, Shitanda T, Matsuyama R, Zafar F, Takahashi TS, Masukata H, Nakagawa T.
Nucleic Acids Research, 44(22):10744-10757. doi: 10.1093/nar/gkw874
MutSα maintains the mismatch repair capability by inhibiting PCNA unloading.
Kawasoe Y, Tsurimoto T, Nakagawa T, Masukata H, Takahashi TS.
eLife, 2016 Jul 12;5. pii: e15155. doi: 10.7554/eLife.15155.
PCNA Retention on DNA into G2/M Phase Causes Genome Instability in Cells Lacking Elg1.
Johnson C, Gali VK, Takahashi TS, Kubota T.
Cell Reports, 16(3):684-95. doi: 10.1016/j.celrep.2016.06.030.
Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells.
Yang CC, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, Fukatsu R, Fujisawa R, Sakimura K, Tsurimoto T, Masai H.
Nature Communications, 7:12135. doi: 10.1038/ncomms12135.
In vivo evidence for translesion synthesis by the replicative DNA polymerase δ.
Hirota K, Tsuda M, Mohiuddin, Tsurimoto T, Cohen IS, Livneh Z, Kobayashi K, Narita T, Nishihara K, Murai J, Iwai S, Guilbaud G, Sale JE, Takeda S.
Nucleic Acids Research, 44(15):7242-50. doi: 10.1093/nar/gkw439.
Rapid Purification and Characterization of Mutant Origin Recognition Complexes in Saccharomyces cerevisiae.
Kawakami H, Ohashi E, Tsurimoto T, Katayama T.
Frontiers in Microbiology, 7:521. doi: 10.3389/fmicb.2016.00521.
Conserved interaction of Ctf18-RFC with DNA polymerase ε is critical for maintenance of genome stability in Saccharomyces cerevisiae.
Okimoto H, Tanaka S, Araki H, Ohashi E, Tsurimoto T.
Genes to Cells, 2016 May;21(5):482-91. doi: 10.1111/gtc.12356.
Specific binding of eukaryotic ORC to DNA replication origins depends on highly conserved basic residues.
Kawakami H, Ohashi E, Kanamoto S, Tsurimoto T, Katayama T.
Scientific Reports, 5:14929. doi: 10.1038/srep14929.
Short CCG repeat in huntingtin gene is an obstacle for replicative DNA polymerases, potentially hampering progression of replication fork.
Le HP, Masuda Y, Tsurimoto T, Maki S, Katayama T, Furukohri A, Maki H.
Genes to Cells, 20(10):817-33. doi: 10.1111/gtc.12275.
Intramolecular Binding of the Rad9 C Terminus in the Checkpoint Clamp Rad9-Hus1-Rad1 Is Closely Linked with Its DNA Binding.
Takeishi Y, Iwaya-Omi R, Ohashi E, Tsurimoto T.
Journal of Biological Chemistry, 290(32):19923-32. doi: 10.1074/jbc.M115.669002.
Reconstitution of mitotic chromatids with a minimum set of purified factors.
Shintomi K, Takahashi TS, Hirano T.
Nature Cell Biology, 17(8):1014-23. doi: 10.1038/ncb3187.
The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ.
Hirota K, Yoshikiyo K, Guilbaud G, Tsurimoto T, Murai J, Tsuda M, Phillips LG, Narita T, Nishihara K, Kobayashi K, Yamada K, Nakamura J, Pommier Y, Lehmann A, Sale JE, Takeda S.
Nucleic Acids Research, 43(3):1671-83. doi: 10.1093/nar/gkv023.
RecQ4 promotes the conversion of the pre-initiation complex at a site-specific origin for DNA unwinding in Xenopus egg extracts.
Sanuki Y, Kubota Y, Kanemaki MT, Takahashi TS, Mimura S, Takisawa H.
Cell Cycle, 14(7):1010-23. doi: 10.1080/15384101.2015.1007003.
Interaction between Rad9-Hus1-Rad1 and TopBP1 activates ATR-ATRIP and promotes TopBP1 recruitment to sites of UV-damage.
Ohashi E, Takeishi Y, Ueda S, Tsurimoto T.
DNA Repair (Amst), 21:1-11. doi: 10.1016/j.dnarep.2014.05.001.
Kaposi's sarcoma-associated herpesvirus LANA recruits the DNA polymerase clamp loader to mediate efficient replication and virus persistence.
Sun Q, Tsurimoto T, Juillard F, Li L, Li S, De León Vázquez E, Chen S, Kaye K.
Proceedings of the National Academy of Sciences of USA, 111(32):11816-21. doi: 10.1073/pnas.1404219111.
Thymine DNA glycosylase is a CRL4Cdt2 substrate.
Slenn TJ, Morris B, Havens CG, Freeman RM Jr, Takahashi TS, Walter JC.
Journal of Biological Chemistry, 289(33):23043-55. doi: 10.1074/jbc.M114.574194.
MutS stimulates the endonuclease activity of MutL in an ATP-hydrolysis-dependent manner.
Shimada A, Kawasoe Y, Hata Y, Takahashi TS, Masui R, Kuramitsu S, Fukui K.
FEBS Journal, 280(14):3467-79. doi: 10.1111/febs.12344. Epub 2013 Jun 18.
RAD5a ubiquitin ligase is involved in ubiquitination of Arabidopsis thaliana proliferating cell nuclear antigen.
Strzalka W, Bartnicki F, Pels K, Jakubowska A, Tsurimoto T, Tanaka K.
Journal of Experimental Botany, 64(4):859-69. doi: 10.1093/jxb/ers368.
Ubiquitin mediates the physical and functional interaction between human DNA polymerases η and ι.
McIntyre J, Vidal AE, McLenigan MP, Bomar MG, Curti E, McDonald JP, Plosky BS, Ohashi E, Woodgate R.
Nucleic Acids Research, 41(3):1649-60. doi: 10.1093/nar/gks1277.
Efficient long DNA gap-filling in a mammalian cell-free system: a potential new in vitro DNA replication assay.
Nakao S, Zhang S, Vaara M, Syväoja JE, Lee MY, Tsurimoto T, Karran P, Oda S.
Biochimie, 95(2):320-8. doi: 10.1016/j.biochi.2012.09.031.
Telomere-binding protein Taz1 controls global replication timing through its localization near late replication origins in fission yeast.
Tazumi A, Fukuura M, Nakato R, Kishimoto A, Takenaka T, Ogawa S, Song JH, Takahashi TS, Nakagawa T, Shirahige K, Masukata H.
Genes&Development, 26(18):2050-62. doi: 10.1101/gad.194282.112.
Two serine phosphorylation sites in the C-terminus of Rad9 are critical for 9-1-1 binding to TopBP1 and activation of the DNA damage checkpoint response in HeLa cells.
Ueda S, Takeishi Y, Ohashi E, Tsurimoto T.
Genes to Cells, 17(10):807-16. doi: 10.1111/j.1365-2443.2012.01630.x.
DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast.
Handa T, Kanke M, Takahashi TS, Nakagawa T, Masukata H.
Molecular Biology of the Cell, 23(16):3240-53. doi: 10.1091/mbc.E12-05-0339.
In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex.
Bermudez VP, Farina A, Higashi TL, Du F, Tappin I, Takahashi TS, Hurwitz J.
Proceedings of the National Academy of Sciences of USA, 109(24):9366-71. doi: 10.1073/pnas.1206840109.
In vitro loading of human cohesin on DNA by the human Scc2-Scc4 loader complex.
Bermudez VP, Farina A, Higashi TL, Du F, Tappin I, Takahashi TS, Hurwitz J.
Proceedings of the National Academy of Sciences of USA, 109(24):9366-71. doi: 10.1073/pnas.1206840109.
The prereplication complex recruits XEco2 to chromatin to promote cohesin acetylation in Xenopus egg extracts.
Higashi TL, Ikeda M, Tanaka H, Nakagawa T, Bando M, Shirahige K, Kubota Y, Takisawa H, Masukata H, Takahashi TS.
Current Biology, 22(11):977-88. doi: 10.1016/j.cub.2012.04.013.
Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components.
Kanke M, Kodama Y, Takahashi TS, Nakagawa T, Masukata H.
EMBO Jouranl, 31(9):2182-94. doi: 10.1038/emboj.2012.68.
The vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled site.
Hashimoto K, Cho Y, Yang IY, Akagi J, Ohashi E, Tateishi S, de Wind N, Hanaoka F, Ohmori H, Moriya M.
Journal of Biological Chemistry, 287(12):9613-22. doi: 10.1074/jbc.M111.331728.
Interaction of heliquinomycin with single-stranded DNA inhibits MCM4/6/7 helicase.
Sugiyama T, Chino M, Tsurimoto T, Nozaki N, Ishimi Y.
Journal of Biochemistry. 151(2):129-37. doi: 10.1093/jb/mvr130.
Abundance of prereplicative complexes (Pre-RCs) facilitates recombinational repair under replication stress in fission yeast.
Maki K, Inoue T, Onaka A, Hashizume H, Somete N, Kobayashi Y, Murakami S, Shigaki C, Takahashi TS, Masukata H, Nakagawa T.
Journal of Biological Chemistry, 286(48):41701-10. doi: 10.1074/jbc.M111.285619.
Werner interacting protein 1 promotes binding of Werner protein to template-primer DNA.
Kanamori M, Seki M, Yoshimura A, Tsurimoto T, Tada S, Enomoto T.
Biological and Pharmaceutical Bulletin, 34(8):1314-8.
CDK promotes interactions of Sld3 and Drc1 with Cut5 for initiation of DNA replication in fission yeast.
Fukuura M, Nagao K, Obuse C, Takahashi TS, Nakagawa T, Masukata H.
Molecular Biology of the Cell, 22(14):2620-33. doi: 10.1091/mbc.E10-12-0995.
Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling.
Hayashi-Takanaka Y, Yamagata K, Wakayama T, Stasevich TJ, Kainuma T, Tsurimoto T, Tachibana M, Shinkai Y, Kurumizaka H, Nozaki N, Kimura H.
Nucleic Acids Research, 39(15):6475-88. doi: 10.1093/nar/gkr343.
Auxin-inducible protein depletion system in fission yeast.
Kanke M, Nishimura K, Kanemaki M, Kakimoto T, Takahashi TS, Nakagawa T, Masukata H.
BMC Cell Biology, 12:8. doi: 10.1186/1471-2121-12-8.
Human replicative DNA polymerase δ can bypass T-T (6-4) ultraviolet photoproducts on template strands.
Narita T, Tsurimoto T, Yamamoto J, Nishihara K, Ogawa K, Ohashi E, Evans T, Iwai S, Takeda S, Hirota K.
Genes to Cells, 15(12):1228-39. doi: 10.1111/j.1365-2443.2010.01457.x.
Stable interaction between the human proliferating cell nuclear antigen loader complex Ctf18-replication factor C (RFC) and DNA polymerase {epsilon} is mediated by the cohesion-specific subunits, Ctf18, Dcc1, and Ctf8.
Murakami T, Takano R, Takeo S, Taniguchi R, Ogawa K, Ohashi E, Tsurimoto T.
Journal of Biological Chemistry, 285(45):34608-15. doi: 10.1074/jbc.M110.166710.
Casein kinase 2-dependent phosphorylation of human Rad9 mediates the interaction between human Rad9-Hus1-Rad1 complex and TopBP1.
Takeishi Y, Ohashi E, Ogawa K, Masai H, Obuse C, Tsurimoto T.
Genes to Cells, 15(7):761-71. doi: 10.1111/j.1365-2443.2010.01418.x.
Overlapping in short motif sequences for binding to human REV7 and MAD2 proteins.
Hanafusa T, Habu T, Tomida J, Ohashi E, Murakumo Y, Ohmori H.
Genes to Cells, 15(3):281-96. doi: 10.1111/j.1365-2443.2009.01380.x.
Physical and functional interaction between WRNIP1 and RAD18.
Yoshimura A, Seki M, Kanamori M, Tateishi S, Tsurimoto T, Tada S, Enomoto T.
Genes & Genetic Systems, 84(2):171-8.
Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases.
Kimura T, Takeuchi T, Kumamoto-Yonezawa Y, Ohashi E, Ohmori H, Masutani C, Hanaoka F, Sugawara F, Yoshida H, Mizushina Y.
Bioorganic & Medicinal Chemistry, 17(5):1811-6. doi: 10.1016/j.bmc.2009.01.064.
Structural basis for novel interactions between human translesion synthesis polymerases and proliferating cell nuclear antigen.
Hishiki A, Hashimoto H, Hanafusa T, Kamei K, Ohashi E, Shimizu T, Ohmori H, Sato M.
Journal of Biological Chemistry, 284(16):10552-60. doi: 10.1074/jbc.M809745200.
The heterochromatin protein Swi6/HP1 activates replication origins at the pericentromeric region and silent mating-type locus.
Hayashi MT, Takahashi TS, Nakagawa T, Nakayama J, Masukata H.
Nature Cell Biology, 11(3):357-62. doi: 10.1038/ncb1845.
Identification of a novel REV1-interacting motif necessary for DNA polymerase kappa function.
Ohashi E, Hanafusa T, Kamei K, Song I, Tomida J, Hashimoto H, Vaziri C, Ohmori H.
Genes to Cells, 14(2):101-11. doi: 10.1111/j.1365-2443.2008.01255.x.
Interaction with DNA polymerase eta is required for nuclear accumulation of REV1 and suppression of spontaneous mutations in human cells.
Akagi J, Masutani C, Kataoka Y, Kan T, Ohashi E, Mori T, Ohmori H, Hanaoka F.
DNA Repair (Amst), 8(5):585-99. doi: 10.1016/j.dnarep.2008.12.006.
Rad51 suppresses gross chromosomal rearrangement at centromere in Schizosaccharomyces pombe.
Nakamura K, Okamoto A, Katou Y, Yadani C, Shitanda T, Kaweeteerawat C, Takahashi TS, Itoh T, Shirahige K, Masukata H, Nakagawa T.
EMBO Journal, 27(22):3036-46. doi: 10.1038/emboj.2008.215.
CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation.
Nishitani H, Shiomi Y, Iida H, Michishita M, Takami T, Tsurimoto T.
Journal of Biological Chemistry, 283(43):29045-52. doi: 10.1074/jbc.M806045200.
Cdc7-Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts.
Takahashi TS, Basu A, Bermudez V, Hurwitz J, Walter JC.
Genes&Development, 22(14):1894-905. doi: 10.1101/gad.1683308.
Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks.
Tsuji Y, Watanabe K, Araki K, Shinohara M, Yamagata Y, Tsurimoto T, Hanaoka F, Yamamura K, Yamaizumi M, Tateishi S.
Genes to Cells, 13(4):343-54. doi: 10.1111/j.1365-2443.2008.01176.x.
DNA damage-induced ubiquitylation of RFC2 subunit of replication factor C complex.
Tomida J, Masuda Y, Hiroaki H, Ishikawa T, Song I, Tsurimoto T, Tateishi S, Shiomi T, Kamei Y, Kim J, Kamiya K, Vaziri C, Ohmori H, Todo T.
Journal of Biological Chemistry, 283(14):9071-9. doi: 10.1074/jbc.M709835200.
Dynamics of human replication factors in the elongation phase of DNA replication.
Masuda Y, Suzuki M, Piao J, Gu Y, Tsurimoto T, Kamiya K.
Nucleic Acids Research, 35(20):6904-16.
A second proliferating cell nuclear antigen loader complex, Ctf18-replication factor C, stimulates DNA polymerase eta activity.
Shiomi Y, Masutani C, Hanaoka F, Kimura H, Tsurimoto T.
Journal of Biological Chemistry, 282(29):20906-14.
Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.
Nishitani H, Sugimoto N, Roukos V, Nakanishi Y, Saijo M, Obuse C, Tsurimoto T, Nakayama KI, Nakayama K, Fujita M, Lygerou Z, Nishimoto T.
EMBO Journal, 25(5):1126-36.
Cdc7-Drf1 is a developmentally regulated protein kinase required for the initiation of vertebrate DNA replication.
Takahashi TS, Walter JC.
Genes&Development, 19(19):2295-300.
Error-prone and inefficient replication across 8-hydroxyguanine (8-oxoguanine) in human and mouse ras gene fragments by DNA polymerase kappa.
Jałoszyński P, Ohashi E, Ohmori H, Nishimura S.
Genes to Cells, 10(6):543-50.
Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase delta.
Tsurimoto T, Shinozaki A, Yano M, Seki M, Enomoto T.
Genes to Cells, 10(1):13-22.
Recruitment of Xenopus Scc2 and cohesin to chromatin requires the pre-replication complex.
Takahashi TS, Yiu P, Chou MF, Gygi S, Walter JC.
Nature Cell Biology, 6(10):991-6.
Rad18 guides poleta to replication stalling sites through physical interaction and PCNA monoubiquitination.
Watanabe K, Tateishi S, Kawasuji M, Tsurimoto T, Inoue H, Yamaizumi M.
EMBO Journal. 23(19):3886-96.
Interaction of hREV1 with three human Y-family DNA polymerases.
Ohashi E, Murakumo Y, Kanjo N, Akagi J, Masutani C, Hanaoka F, Ohmori H.
Genes to Cells, 9(6):523-31.
The reconstituted human Chl12-RFC complex functions as a second PCNA loader.
Shiomi Y, Shinozaki A, Sugimoto K, Usukura J, Obuse C, Tsurimoto T.
Genes to Cells, 9(4):279-90.
Sequence context-dependent replication of DNA templates containing UV-induced lesions by human DNA polymerase iota.
Vaisman A, Frank EG, Iwai S, Ohashi E, Ohmori H, Hanaoka F, Woodgate R.
DNA Repair (Amst), 2(9):991-1006.
The ORC1 cycle in human cells: I. cell cycle-regulated oscillation of human ORC1.
Tatsumi Y, Ohta S, Kimura H, Tsurimoto T, Obuse C.
Journal of Biological Chemistry, 278(42):41528-34.
The ORC1 cycle in human cells: II. Dynamic changes in the human ORC complex during the cell cycle.
Ohta S, Tatsumi Y, Fujita M, Tsurimoto T, Obuse C.
Journal of Biological Chemistry, 278(42):41535-40.
Multiple ORC-binding sites are required for efficient MCM loading and origin firing in fission yeast.
Takahashi T, Ohara E, Nishitani H, Masukata H.
EMBO Journal, 22(4):964-74.
Translesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iota.
Frank EG, Sayer JM, Kroth H, Ohashi E, Ohmori H, Jerina DM, Woodgate R.
Nucleic Acids Research, 30(23):5284-92.
PCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNA.
Iida T, Suetake I, Tajima S, Morioka H, Ohta S, Obuse C, Tsurimoto T.
Genes Cells. 7(10):997-1007.
A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein.
Ohta S, Shiomi Y, Sugimoto K, Obuse C, Tsurimoto T.
Journal of Biological Chemistry, 277(43):40362-7.
Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9-1-1 and Rad17-RFC.
Shiomi Y, Shinozaki A, Nakada D, Sugimoto K, Usukura J, Obuse C, Tsurimoto T.
Genes to Cells, 7(8):861-8.
Translesion synthesis by human DNA polymerase kappa on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N(2)-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene).
Suzuki N, Ohashi E, Kolbanovskiy A, Geacintov NE, Grollman AP, Ohmori H, Shibutani S.
Biochemistry, 41(19):6100-6.
Scheduled conversion of replication complex architecture at replication origins of Saccharomyces cerevisiae during the cell cycle.
Tadokoro R, Fujita M, Miura H, Shirahige K, Yoshikawa H, Tsurimoto T, Obuse C.
Journal of Biological Chemistry, 277(18):15881-9.
Translesional synthesis past acetylaminofluorene-derived DNA adducts catalyzed by human DNA polymerase kappa and Escherichia coli DNA polymerase IV.
Suzuki N, Ohashi E, Hayashi K, Ohmori H, Grollman AP, Shibutani S.
Biochemistry, 40(50):15176-83.
Interaction of fission yeast ORC with essential adenine/thymine stretches in replication origins.
Takahashi T, Masukata H.
Genes to Cells, 6(10):837-49.
Functional interactions of an archaeal sliding clamp with mammalian clamp loader and DNA polymerase delta.
Ishino Y, Tsurimoto T, Ishino S, Cann IK.
Genes to Cells, 6(8):699-706.
In vitro reconstitution of the end replication problem.
Ohki R, Tsurimoto T, Ishikawa F.
Molecular and Cellular Biology, 21(17):5753-66.
Translesion DNA synthesis catalyzed by human pol eta and pol kappa across 1,N6-ethenodeoxyadenosine.
Levine RL, Miller H, Grollman A, Ohashi E, Ohmori H, Masutani C, Hanaoka F, Moriya M.
Journal of Biological Chemistry, 276(22):18717-21.
The human homologue of fission Yeast cdc27, p66, is a component of active human DNA polymerase delta.
Shikata K, Ohta S, Yamada K, Obuse C, Yoshikawa H, Tsurimoto T.
Journal of Biochemistry, 129(5):699-708.
ATP-dependent structural change of the eukaryotic clamp-loader protein, replication factor C.
Shiomi Y, Usukura J, Masamura Y, Takeyasu K, Nakayama Y, Obuse C, Yoshikawa H, Tsurimoto T.
Proceedings of the National Academy of Sciences of USA, 97(26):14127-32.
Atomic force microscopy with carbon nanotube probe resolves the subunit organization of protein complexes.
Hohmura KI, Itokazu Y, Yoshimura SH, Mizuguchi G, Masamura YS, Takeyasu K, Shiomi Y, Tsurimoto T, Nishijima H, Akita S, Nakayama Y.
Journal of electron microscopy (Tokyo), 49(3):415-21.
Fidelity and processivity of DNA synthesis by DNA polymerase kappa, the product of the human DINB1 gene.
Ohashi E, Bebenek K, Matsuda T, Feaver WJ, Gerlach VL, Friedberg EC, Ohmori H, Kunkel TA.
Journal of Biological Chemistry, 275(50):39678-84.
Error-prone bypass of certain DNA lesions by the human DNA polymerase kappa.
Ohashi E, Ogi T, Kusumoto R, Iwai S, Masutani C, Hanaoka F, Ohmori H.
Genes&Development, 14(13):1589-94.
Association of human origin recognition complex 1 with chromatin DNA and nuclease-resistant nuclear structures.
Tatsumi Y, Tsurimoto T, Shirahige K, Yoshikawa H, Obuse C.
Journal of Biochemistry, 275(8):5904-10.
Functions of Multiple Clamp and Clamp-Loader Complexes in Eukaryotic DNA Replication.
Ohashi E, Tsurimoto T.
Advances in Experimental Medicine and Biology, 1042:135-162. doi: 10.1007/978-981-10-6955-0_7. (2017)
真核生物の染色体複製における多重クランプ・クランプローダー系の役割 塩見泰史、釣本敏樹 生化学 81-5, 10-13 (2009)
複製フォーク制御とDNA損傷／複製ストレス応答機構：概論 釣本敏樹 蛋白質核酸酵素 査読無（特集「染色体サイクル」編 正井久雄ほか）54-4, 370-373 共立出版 (2009)
クランプとクランプローダーによる複製フォーク機能制御 釣本敏樹 蛋白質核酸酵素 特集「染色体サイクル、編 正井久雄ほか」374-379 (2009)
Separate roles of structured and unstructured regions of Y-family DNA polymerases.
Ohmori H, Hanafusa T, Ohashi E, Vaziri C.
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