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Publication List

投稿論文 (最近5年間)

  1. Tsuda M, Terada K, Ooka M, Kobayashi K, Sasanuma H, Fujisawa R, Tsurimoto T, Yamamoto J, Iwai S, Kadoda K, Akagawa R, Huang SN, Pommier Y, Sale JE, Takeda S, Hirota K. (2017) The dominant role of proofreading exonuclease activity of replicative polymerase ε in cellular tolerance to cytarabine (Ara-C). Oncotarget. 8, 33457-33474
  2. Fujisawa R, Ohashi E, Hirota K, Tsurimoto T. (2017) Human CTF18-RFC clamp-loader complexed with non-synthesising DNA polymerase ε efficiently loads the PCNA sliding clamp. Nucleic Acids Res. 45, 4550-4563
  3. MutSα maintains the mismatch repair capability by inhibiting PCNA unloading. Kawasoe Y, Tsurimoto T, Nakagawa T, Masukata H, Takahashi TS. 2016, Elife. 5, e15155.
  4. Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells. Yang CC, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, Fukatsu R, Fujisawa R, Sakimura K, Tsurimoto T, Masai H. 2016, Nat Commun. 7, 12135.
  5. In vivo evidence for translesion synthesis by the replicative DNA polymerase δ. Hirota K, Tsuda M, Mohiuddin, Tsurimoto T, Cohen IS, Livneh Z, Kobayashi K, Narita T, Nishihara K, Murai J, Iwai S, Guilbaud G, Sale JE, Takeda S. 2016, Nucleic Acids Res. 44, 7242-7250.
  6. Rapid purification and characterization of mutant Origin Recognition Complexes in Saccharomyces cerevisiae. Kawakami H, Ohashi E, Kawamoto S, Tsurimoto T, Katayama, T. Front. Microbiol , 2016, 7, 521 /fmicb.2016.00521.
  7. Conserved interaction of Ctf18-RFC with DNA polymerase εis critical for maintenace of genome stability in Saccharomyces cerevisiae. Okimoto H, Tanaka S, Araki H, Ohashi E, Tsurimoto T. Genes Cells. 2016 482-491
  8. Specific binding of eukaryotic ORC to DNA replication origins depends on highly conserved basic residues. Kawakami H, Ohashi E, Kawamoto S, Tsurimoto T, Katayama, T. Scientific Reports, 2015, 5, 14929
  9. Short CCG repeat in huntingtin gene is an obstacle for replicative DNA polymerases, potentially hampering progression of replication fork. Le HP, Masuda Y, Tsurimoto T, Maki S, Katayama T, Furukohri A, Maki H. Genes Cells. 2015, 20, 817-833.
  10. Intramolecular Binding of the Rad9 C Terminus in the Checkpoint Clamp Rad9-Hus1-Rad1 Is Closely Linked with Its DNA Binding. Takeishi Y, Iwaya-Omi R, Ohashi E, Tsurimoto T. J Biol Chem. 2015, 290,19923-19932.
  11. The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ. Hirota K, Yoshikiyo K, Guilbaud G, Tsurimoto T, Murai J, Tsuda M, Phillips LG, Narita T, Nishihara K, Kobayashi K, Yamada K, Nakamura J, Pommier Y, Lehmann A, Sale JE, Takeda S. Nucleic Acids Res. 2015, 43, 1671-168. 3
  12. Interaction between Rad9-Hus1-Rad1 and TopBP1 activates ATR-ATRIP and promotes TopBP1 recruitment to sites of UV-damage. Ohashi E, Takeishi Y, Ueda S, Tsurimoto T. DNA Repair. 2014 21, 1-11.
  13. Kaposi's sarcoma-associated herpesvirus LANA recruits the DNA polymerase clamp loader to mediate efficient replication and virus persistence. Sun Q, Tsurimoto T, Juillard F, Li L, Li S, De León Vázquez E, Chen S, Kaye K. Proc Natl Acad Sci U S A. 2014, 111, 11816-11821.
  14. RAD5a ubiquitin ligase is involved in ubiquitination of Arabidopsis thaliana proliferating cell nuclear antigen Strzalka W, Bartnicki F, Pels K, Jakubowska A, Tsurmoto T, Tanaka K. J. Exp. Bot, 2013, 64, 859-869
  15. Two serine phosphorylation sites in the C-terminus of Rad9 are critical for 9-1-1 binding to TopBP1 and activation of the DNA damage checkpoint response in HeLa cells. Ueda S, Takeishi Y, Ohashi E, Tsurmoto T. Genes Cells 2012, 17, 807-816
  16. EBNA1-dependent recruitment of Orc on OriP of Epstein-Barr Virus with purified proteins: Stimulation by Cdc6 through its direct interaction with EBNA1. Moriyama K, Yoshizawa-Sugata N, Obuse C, Tsurmoto T, Masai H. J. Biol. Chem. 2012, 287, 23977-23994
  17. Interaction of heliquinomycin with single-stranded DNA inhibits MCM4/6/7 helicase.  Sugiyama T, Chino M, Tsurmoto T, Nozaki N, Ishimi Y. J. Biochem, 2012, 151, 129-137


  1. Functions of multiple clamp and clamp-loader complexes in eukaryotic DNA replication Ohashi E and Tsurimoto T. (2017) "DNA Replication: From Old Principles to New Discovery” Advances in Experimental Medicine and Biology, Springer. ed. Masai H and Foiani M.

  2. 真核生物の染色体複製における多重クランプ・クランプローダー系の役割 塩見泰史、釣本敏樹 生化学  81-5, 10-13 (2009)
  3. 複製フォーク制御とDNA損傷/複製ストレス応答機構:概論 釣本敏樹 蛋白質核酸酵素 査読無(特集「染色体サイクル」編 正井久雄ほか)54-4, 370-373 共立出版 (2009)
  4. クランプとクランプローダーによる複製フォーク機能制御 釣本敏樹 蛋白質核酸酵素 特集「染色体サイクル、編 正井久雄ほか」374-379 (2009)